4-Methylcyclohexylamine → Tert-butyl 3-((2-(cis-4-methylcyclohexylamino)-5-bromopyrimidin-4-yloxy)methyl)azetidine-1-carboxylate
Reaction equation
[Br:1][c:2]1[c:3]([O:9][CH2:10][CH:11]2[CH2:12][N:13]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:14]2)[n:4][c:5]([Cl:8])[n:6][cH:7]1.[CH3:22][CH:23]1[CH2:24][CH2:25][CH:26]([NH2:29])[CH2:27][CH2:28]1>>[Br:1][c:2]1[c:3]([O:9][CH2:10][CH:11]2[CH2:12][N:13]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:14]2)[n:4][c:5]([NH:29][CH:26]2[CH2:25][CH2:24][CH:23]([CH3:22])[CH2:28][CH2:27]2)[n:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-6162eb8459384a58bf9c6435c103565d
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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