3-Fluoro-4-piperazin-1-yl-benzonitrile → 3-Fluoro-4-[4-(5-methanesulfonyl-2-thiazol-2-yl-benzoyl)-piperazin-1-yl]-benzonitrile
Reaction equation
[CH3:16][S:17](=[O:18])(=[O:19])[c:20]1[cH:21][cH:22][c:23](-[c:29]2[s:30][cH:31][cH:32][n:33]2)[c:24]([C:25](=[O:26])[OH:27])[cH:28]1.[F:1][c:2]1[cH:3][c:4]([C:5]#[N:6])[cH:7][cH:8][c:9]1[N:10]1[CH2:11][CH2:12][NH:13][CH2:14][CH2:15]1>>[F:1][c:2]1[cH:3][c:4]([C:5]#[N:6])[cH:7][cH:8][c:9]1[N:10]1[CH2:11][CH2:12][N:13]([C:25]([c:24]2[c:23](-[c:29]3[s:30][cH:31][cH:32][n:33]3)[cH:22][cH:21][c:20]([S:17]([CH3:16])(=[O:18])=[O:19])[cH:28]2)=[O:26])[CH2:14][CH2:15]1Participants
3
Sources & evidence
- ORD record
- ord-6f73af420bae4d5097b94a9de05b58b3
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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