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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 957646Generated: October 25, 2026

Hydrochloric Acid → 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidin-4-amine

https://huagongshe.com/reaction/957646

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantMethanolHCID 887—
ReactantTetrahydrofuranHCID 8028—
Reactant1,4-DioxaneHCID 31275—
ReactantN-tert-butyl-N-[1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperidin-4-yl]carbamateHCID 86625872—
Product1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidin-4-amineHCID 2796185—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-1c680a9165bf4a1da5989e45714e4978
Source noteValidation data from https://doi.org/10.1039/C8SC04228D