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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 957767Generated: October 30, 2026

Dimethylformamide → 3-tert-butoxycarbonyl-7-chloro-6-[2-(cyclopropylmethyl-amino)-thiazol-5-ylthiomethyl]-2,3,4,5-tetrahydro-1H-benzo[d]azepine

https://huagongshe.com/reaction/957767

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantCarbonate IonHCID 19660—
ReactantCesium cationHCID 104967—
Reactant3-tert-Butoxycarbonyl-7-chloro-6-mercaptomethyl-2,3,4,5-tetrahydro-1H-benzo[d]azepineHCID 59822276—
ReactantN-(5-bromothiazol-2-yl)-cyclopropylmethylamineHCID 59822318—
Product3-tert-butoxycarbonyl-7-chloro-6-[2-(cyclopropylmethyl-amino)-thiazol-5-ylthiomethyl]-2,3,4,5-tetrahydro-1H-benzo[d]azepineHCID 86623706—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-4ee044cc302f4ad2a24be4b678cd1bd1
Source noteValidation data from https://doi.org/10.1039/C8SC04228D