Ethanol → 2-(2-Methyl-5-nitroanilino)-4-(3-pyridyl)pyrimidine

HRID 957869Notes

Reaction equation

HRID 957869 reaction equation
[C:29](=[O:30])([O-:31])[O-:32].[CH3:1][c:2]1[c:3]([NH:11][c:12]2[n:13][cH:14][c:15]([C:24]([O:25][CH2:26][CH3:27])=[O:28])[c:16](-[c:18]3[cH:19][n:20][cH:21][cH:22][cH:23]3)[n:17]2)[cH:4][c:5]([N+:8](=[O:9])[O-:10])[cH:6][cH:7]1.[CH3:36][CH2:37][OH:38].[K+:33].[K+:34].[OH2:35]>>[CH3:1][c:2]1[c:3]([NH:11][c:12]2[n:13][cH:14][cH:15][c:16](-[c:18]3[cH:19][n:20][cH:21][cH:22][cH:23]3)[n:17]2)[cH:4][c:5]([N+:8](=[O:9])[O-:10])[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 702EthanolHCID 813Potassium Cation2×HCID 962WaterHCID 19660Carbonate IonHCID 592536665-Pyrimidinecarboxylic acid, 2-[(2-methyl-5-nitrophenyl)amino]-4-(3-pyridinyl)-, ethyl ester

Product 1

HCID 106861492-(2-Methyl-5-nitroanilino)-4-(3-pyridyl)pyrimidine

Sources & evidence

ORD record
ord-e1e2db065ef743d4a8c4c7b350f310c1
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…