Ethylene Glycol → 6-fluoro-3-(piperidin-4-yl)-1H-indole
Reaction equation
[C:1](=[O:2])([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[N:9]1[CH2:10][CH2:11][CH:12]([c:15]2[cH:16][nH:17][c:18]3[cH:19][c:20]([F:24])[cH:21][cH:22][c:23]23)[CH2:13][CH2:14]1.[CH2:27]([OH:28])[CH2:29][OH:30].[K+:26].[OH-:25].[OH2:31]>>[NH:9]1[CH2:10][CH2:11][CH:12]([c:15]2[cH:16][nH:17][c:18]3[cH:19][c:20]([F:24])[cH:21][cH:22][c:23]23)[CH2:13][CH2:14]1Participants
6
Sources & evidence
- ORD record
- ord-fb2a391ec6fb4e88a4a9f8cfff578362
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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