1-(Methylsulfonyl)piperazine → [1-Isopropoxy-3-(5-methyl-1H-pyrazol-3-ylamino)-isoquinolin-6-yl]-(4-methanesulfonyl-piperazin-1-yl)-methanone
Reaction equation
[CH3:25][S:26](=[O:27])(=[O:28])[N:29]1[CH2:30][CH2:31][NH:32][CH2:33][CH2:34]1.[CH:1]([CH3:2])([CH3:3])[O:4][c:5]1[n:6][c:7]([NH:18][c:19]2[n:20][nH:21][c:22]([CH3:24])[cH:23]2)[cH:8][c:9]2[cH:10][c:11]([C:15](=[O:16])[OH:17])[cH:12][cH:13][c:14]12>>[CH:1]([CH3:2])([CH3:3])[O:4][c:5]1[n:6][c:7]([NH:18][c:19]2[n:20][nH:21][c:22]([CH3:24])[cH:23]2)[cH:8][c:9]2[cH:10][c:11]([C:15](=[O:17])[N:32]3[CH2:31][CH2:30][N:29]([S:26]([CH3:25])(=[O:27])=[O:28])[CH2:34][CH2:33]3)[cH:12][cH:13][c:14]12Participants
3
Sources & evidence
- ORD record
- ord-32d1e473b56a4999ad8b6e33abdb2652
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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