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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 958247Generated: October 26, 2026

2-[8-(Benzothiazol-2-ylcarbamoyl)-3,4-dihydro-1H-isoquinolin-2-yl]-5-{3-[4-(4-cyano-thiophen-3-yl)-phenoxy]-propyl]-thiazole-4-carboxylic acid → 2-[8-(Benzothiazol-2-ylcarbamoyl)-3,4-dihydro-1H-isoquinolin-2-yl]-5-(2-phenyl-azetidin-1-ylmethyl)-thiazole-4-carboxylic acid

https://huagongshe.com/reaction/958247

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[8-(Benzothiazol-2-ylcarbamoyl)-3,4-dihydro-1H-isoquinolin-2-yl]-5-{3-[4-(4-cyano-thiophen-3-yl)-phenoxy]-propyl]-thiazole-4-carboxylic acidHCID 46836245—
Reactantmethyl 5-[(2-phenylazetidin-1-yl)methyl]-2-[8-[2-[3-(2-trimethylsilylethoxymethyl)-1,3-benzothiazol-2-ylidene]acetyl]-3,4-dihydro-1H-isoquinolin-2-yl]-1,3-thiazole-4-carboxylateHCID 67430836—
Product2-[8-(Benzothiazol-2-ylcarbamoyl)-3,4-dihydro-1H-isoquinolin-2-yl]-5-(2-phenyl-azetidin-1-ylmethyl)-thiazole-4-carboxylic acidHCID 46836573—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-d7e9216076f14072abe02036f8975a0e
Source noteValidation data from https://doi.org/10.1039/C8SC04228D