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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 958358Generated: October 31, 2026

Dimethyl Sulfoxide → 4-Cyano-4-(4-iodo-phenyl)-piperidine-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/958358

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl SulfoxideHCID 679—
ReactantEthyl AcetateHCID 8857—
Reactant4-IodophenylacetonitrileHCID 142866—
ReactantN-BOC-N,N-Bis(2-chloroethyl)amineHCID 11230235—
Product4-Cyano-4-(4-iodo-phenyl)-piperidine-1-carboxylic acid tert-butyl esterHCID 20779475—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-3f20bf044f544eacb80fb79481b3b65c
Source noteValidation data from https://doi.org/10.1039/C8SC04228D