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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 958427Generated: October 26, 2026

Methanol → 4-[[5-[tert-butyl(dimethyl)silyl]oxy-2-fluorophenyl]-(2,5-dimethylpiperazin-1-yl)methyl]-N,N-diethylbenzamide

https://huagongshe.com/reaction/958427

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantDichloromethaneHCID 6344—
Reactant2,5-DimethylpiperazineHCID 7816—
ReactantThionyl ChlorideHCID 24386—
Reactant4-(5-(tert-butyldimethylsilyloxy)-2-fluoro-alpha-hydroxybenzyl)-N,N-diethylbenzamideHCID 54114191—
Product4-[[5-[tert-butyl(dimethyl)silyl]oxy-2-fluorophenyl]-(2,5-dimethylpiperazin-1-yl)methyl]-N,N-diethylbenzamideHCID 69941893—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-bbb145d1474f492198f2c7b83cbf3651
Source noteValidation data from https://doi.org/10.1039/C8SC04228D