Methanol → 6-(4-chloro-1H-imidazol-1-yl)pyridin-3-amine

HRID 958441Notes

Reaction equation

HRID 958441 reaction equation
[CH3:21][OH:22].[Cl:1][c:2]1[n:3][cH:4][n:5](-[c:7]2[n:8][cH:9][c:10]([N+:13]([O-:14])=[O:15])[cH:11][cH:12]2)[cH:6]1.[OH2:16].[OH2:17].[Sn:18]([Cl:19])[Cl:20]>>[Cl:1][c:2]1[n:3][cH:4][n:5](-[c:7]2[n:8][cH:9][c:10]([NH2:13])[cH:11][cH:12]2)[cH:6]1

Participants

5

Reactant 4

HCID 887MethanolHCID 962Water2×HCID 24479Stannous ChlorideHCID 68156857HCID 68156857, compound

Product 1

HCID 681575046-(4-chloro-1H-imidazol-1-yl)pyridin-3-amine

Sources & evidence

ORD record
ord-8aca289d98134f12ab9e17ae53dadf8a
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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