Toluene → HCID 58829668, compound

HRID 958488Notes

Reaction equation

HRID 958488 reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([P:7]2(=[S:10])[S:8][P:9]([c:11]3[cH:12][cH:13][c:14]([O:15][CH3:16])[cH:17][cH:18]3)(=[S:19])[S:20]2)[cH:21][cH:22]1.[CH3:56][c:57]1[cH:58][cH:59][cH:60][cH:61][cH:62]1.[F:23][c:24]1[c:25]([C:26](=[O:27])[NH:28][c:29]2[cH:30][c:31]([O:35][CH:36]([CH3:37])[CH3:38])[cH:32][cH:33][cH:34]2)[cH:39][cH:40][c:41]([CH3:55])[c:42]1-[c:43]1[cH:44][c:45]2[cH:46][n:47][c:48]([NH:53][CH3:54])[n:49][c:50]2[cH:51][cH:52]1>>[S:10]=[C:26]([c:25]1[c:24]([F:23])[c:42](-[c:43]2[cH:44][c:45]3[cH:46][n:47][c:48]([NH:53][CH3:54])[n:49][c:50]3[cH:51][cH:52]2)[c:41]([CH3:55])[cH:40][cH:39]1)[NH:28][c:29]1[cH:30][c:31]([O:35][CH:36]([CH3:37])[CH3:38])[cH:32][cH:33][cH:34]1

Participants

4

Reactant 3

HCID 1140TolueneHCID 87949Lawesson's reagentHCID 588290582-fluoro-N-(3-isopropoxyphenyl)-4-methyl-3-(2-(methylamino)quinazolin-6-yl)benzamide

Product 1

HCID 58829668HCID 58829668, compound

Sources & evidence

ORD record
ord-8036ad07bd0547bebcad6cef949ae8cd
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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