8-bromo-1-(3-chloro-1-methyl-1H-pyrazol-4-yl)-3-methyl-1,3-dihydro-imidazo[4,5-c]quinolin-2-one → 1-(3-Chloro-1-methyl-1H-pyrazol-4-yl)-8-(5-ethylamino-6-methoxy-pyridin-3-yl)-3-methyl-1,3-dihydro-imidazo[4,5-c]quinolin-2-one

HRID 958890Notes

Reaction equation

HRID 958890 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]3[c:6]([cH:7][n:8][c:9]2[cH:10][cH:11]1)[n:12]([CH3:23])[c:13](=[O:22])[n:14]3-[c:15]1[c:16]([Cl:21])[n:17][n:18]([CH3:20])[cH:19]1.[CH2:24]([CH3:25])[NH:26][c:27]1[c:28]([O:42][CH3:43])[n:29][cH:30][c:31]([B:33]2[O:34][C:35]([CH3:36])([CH3:37])[C:38]([CH3:39])([CH3:40])[O:41]2)[cH:32]1>>[c:2]1(-[c:31]2[cH:30][n:29][c:28]([O:42][CH3:43])[c:27]([NH:26][CH2:24][CH3:25])[cH:32]2)[cH:3][c:4]2[c:5]3[c:6]([cH:7][n:8][c:9]2[cH:10][cH:11]1)[n:12]([CH3:23])[c:13](=[O:22])[n:14]3-[c:15]1[c:16]([Cl:21])[n:17][n:18]([CH3:20])[cH:19]1

Participants

3

Reactant 2

HCID 596197258-bromo-1-(3-chloro-1-methyl-1H-pyrazol-4-yl)-3-methyl-1,3-dihydro-imidazo[4,5-c]quinolin-2-oneHCID 59620014N-ethyl-2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-amine

Product 1

HCID 498356181-(3-Chloro-1-methyl-1H-pyrazol-4-yl)-8-(5-ethylamino-6-methoxy-pyridin-3-yl)-3-methyl-1,3-dihydro-imidazo[4,5-c]quinolin-2-one

Sources & evidence

ORD record
ord-4ddc7bf1cecd4147b503690209fd2ce6
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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