1-[2-(2,2,2-Trifluoroethoxy)phenyl]piperazine → 2-(3-{4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl}propyl)-6-methyl-4-[2-(trimethylsilyl)ethoxymethyl]-1,2,4-triazine-3,5(2H,4H)-dione
Reaction equation
[Cl:19][CH2:20][CH2:21][CH2:22][n:23]1[n:24][c:25]([CH3:39])[c:26](=[O:38])[n:27]([CH2:30][O:31][CH2:32][CH2:33][Si:34]([CH3:35])([CH3:36])[CH3:37])[c:28]1=[O:29].[F:1][C:2]([CH2:3][O:4][c:5]1[c:6]([N:11]2[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]2)[cH:7][cH:8][cH:9][cH:10]1)([F:17])[F:18]>>[F:1][C:2]([CH2:3][O:4][c:5]1[c:6]([N:11]2[CH2:12][CH2:13][N:14]([CH2:20][CH2:21][CH2:22][n:23]3[n:24][c:25]([CH3:39])[c:26](=[O:38])[n:27]([CH2:30][O:31][CH2:32][CH2:33][Si:34]([CH3:35])([CH3:36])[CH3:37])[c:28]3=[O:29])[CH2:15][CH2:16]2)[cH:7][cH:8][cH:9][cH:10]1)([F:17])[F:18]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-8fc23eae4a5f474682b01750e85b3dac
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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