3-Bromo-2,4-difluoroaniline → 3'-Amino-6,2',6'-trifluorobiphenyl-2-carbonitrile
Reaction equation
[Br:1][c:2]1[c:3]([F:10])[c:4]([NH2:9])[cH:5][cH:6][c:7]1[F:8].[F:11][c:12]1[c:13]([B:20]2[O:21][C:22]([CH3:23])([CH3:24])[C:25]([CH3:26])([CH3:27])[O:28]2)[c:14]([C:15]#[N:16])[cH:17][cH:18][cH:19]1>>[c:2]1(-[c:13]2[c:12]([F:11])[cH:19][cH:18][cH:17][c:14]2[C:15]#[N:16])[c:3]([F:10])[c:4]([NH2:9])[cH:5][cH:6][c:7]1[F:8]Participants
3
Sources & evidence
- ORD record
- ord-4d9bd005a8924a03abe6f6f491dac729
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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