5-Chloro-2-thiophenecarboxylic acid → HCID 42643120, compound

HRID 959302Notes

Reaction equation

HRID 959302 reaction equation
[Cl:24][c:25]1[cH:26][cH:27][c:28]([C:30](=[O:31])[OH:32])[s:29]1.[NH2:1][c:2]1[s:3][cH:4][c:5]([CH2:7][C:8](=[O:9])[N:10]2[CH2:11][CH2:12][N:13]([CH2:16][C:17]([N:18]3[CH2:19][CH2:20][CH2:21][CH2:22]3)=[O:23])[CH2:14][CH2:15]2)[n:6]1>>[NH:1]([c:2]1[s:3][cH:4][c:5]([CH2:7][C:8](=[O:9])[N:10]2[CH2:11][CH2:12][N:13]([CH2:16][C:17]([N:18]3[CH2:19][CH2:20][CH2:21][CH2:22]3)=[O:23])[CH2:14][CH2:15]2)[n:6]1)[C:30]([c:28]1[cH:27][cH:26][c:25]([Cl:24])[s:29]1)=[O:31]

Participants

3

Reactant 2

HCID 950485-Chloro-2-thiophenecarboxylic acidHCID 596988402-(2-Amino-thiazol-4-yl)-1-[4-(2-oxo-2-pyrrolidin-1-yl-ethyl)-piperazin-1-yl]-ethanone

Product 1

HCID 42643120HCID 42643120, compound

Sources & evidence

ORD record
ord-5656482435cb4d8f81c03db74792db01
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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