HRID959323

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2776518

4-(bromomethyl)-3-methyl-5-phenylisoxazole

C11H10BrNO

结构：CC(C)(C)OC(=O)CN1C(=O)C2(CC(=O)N(Cc3ccccc3F)C2)c2cc(Cl)ccc21

HCID58017127

未命名化合物

PRODUCTS

生成物

结构：Cc1noc(-c2ccccc2)c1CN1CC2(CC1=O)C(=O)N(CC(=O)OC(C)(C)C)c1ccc(Cl)cc12

HCID24827316

tert-butyl [5-chloro-1'-[(3-methyl-5-phenylisoxazol-4-yl)methyl]-2,5'-dioxospiro[indole-3,3'-pyrrolidin]-1(2H)-yl]acetate

C28H28ClN3O5

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-975886b477a3420c9185a1ee8ba5c631
来源数据集: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Validation data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[Br:33][CH2:34][c:35]1[c:36]([CH3:46])[n:37][o:38][c:39]1-[c:40]1[cH:41][cH:42][cH:43][cH:44][cH:45]1.[Cl:1][c:2]1[cH:3][c:4]2[c:8]([cH:9][cH:10]1)[N:7]([CH2:11][C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[C:6](=[O:19])[C:5]21[CH2:20][N:21]([CH2:25][c:26]2[cH:27][cH:28][cH:29][cH:30][c:31]2[F:32])[C:22](=[O:24])[CH2:23]1>>[Cl:1][c:2]1[cH:3][c:4]2[c:8]([cH:9][cH:10]1)[N:7]([CH2:11][C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[C:6](=[O:19])[C:5]21[CH2:20][N:21]([CH2:25][c:35]2[c:36]([CH3:46])[n:37][o:38][c:39]2-[c:40]2[cH:41][cH:42][cH:43][cH:44][cH:45]2)[C:22](=[O:24])[CH2:23]1