Methoxycarbonylamino-o-tolyl-acetic acid → [1-(2-{5-[6-(4-{2-[1-(2-Methoxycarbonylamino-2-o-tolyl-acetyl)-pyrrolidin-2-yl]-3H-imidazol-4-yl}-phenyl)-naphthalen-2-yl]-1H-imidazol-2-yl}-pyrrolidine-1-carbonyl)-2-methyl-propyl]-carbamic acid methyl ester
Reaction equation
[CH3:1][O:2][C:3]([NH:4][CH:5]([CH:6]([CH3:7])[CH3:8])[C:9](=[O:10])[N:11]1[CH:12]([c:16]2[nH:17][c:18](-[c:21]3[cH:22][c:23]4[cH:24][cH:25][c:26](-[c:31]5[cH:32][cH:33][c:34](-[c:37]6[nH:38][c:39]([CH:42]7[N:43]([C:47]([CH:48]([c:49]8[cH:50][cH:51][cH:52][cH:53][cH:54]8)[NH:55][C:56](=[O:57])[O:58][CH3:59])=[O:60])[CH2:44][CH2:45][CH2:46]7)[n:40][cH:41]6)[cH:35][cH:36]5)[cH:27][c:28]4[cH:29][cH:30]3)[cH:19][n:20]2)[CH2:13][CH2:14][CH2:15]1)=[O:61].[CH3:62][O:63][C:64]([NH:65][CH:66]([c:67]1[cH:68][cH:69][cH:70][cH:71][c:72]1[CH3:73])[C:74]([OH:75])=[O:76])=[O:77]>>[CH3:1][O:2][C:3]([NH:4][CH:5]([CH:6]([CH3:7])[CH3:8])[C:9](=[O:10])[N:11]1[CH:12]([c:16]2[nH:17][c:18](-[c:21]3[cH:22][c:23]4[cH:24][cH:25][c:26](-[c:31]5[cH:32][cH:33][c:34](-[c:37]6[nH:38][c:39]([CH:42]7[N:43]([C:47]([CH:48]([c:49]8[c:50]([CH3:62])[cH:51][cH:52][cH:53][cH:54]8)[NH:55][C:56](=[O:57])[O:58][CH3:59])=[O:60])[CH2:44][CH2:45][CH2:46]7)[n:40][cH:41]6)[cH:35][cH:36]5)[cH:27][c:28]4[cH:29][cH:30]3)[cH:19][n:20]2)[CH2:13][CH2:14][CH2:15]1)=[O:61]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-87a7e39a2df24f2192f6ef374735c9b6
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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