Methanesulfonamide → N-(4-chloro-3-(pyridin-2-yl)phenyl)-6-(methylsulfonamido)nicotinamide

HRID 959517Notes

Reaction equation

HRID 959517 reaction equation
[C:29]([N:30]=[P:31]1([N:32]([CH2:33][CH3:34])[CH2:35][CH3:36])[N:37]([CH3:38])[CH2:39][CH2:40][CH2:41][N:42]1[CH3:43])([CH3:44])([CH3:45])[CH3:46].[CH3:24][S:25](=[O:26])(=[O:27])[NH2:28].[Cl:1][c:2]1[n:3][cH:4][c:5]([C:6](=[O:7])[NH:8][c:9]2[cH:10][c:11](-[c:16]3[n:17][cH:18][cH:19][cH:20][cH:21]3)[c:12]([Cl:15])[cH:13][cH:14]2)[cH:22][cH:23]1>>[c:2]1([NH:28][S:25]([CH3:24])(=[O:26])=[O:27])[n:3][cH:4][c:5]([C:6](=[O:7])[NH:8][c:9]2[cH:10][c:11](-[c:16]3[n:17][cH:18][cH:19][cH:20][cH:21]3)[c:12]([Cl:15])[cH:13][cH:14]2)[cH:22][cH:23]1

Participants

4

Reactant 3

HCID 72879MethanesulfonamideHCID 35138512-((1,1-Dimethylethyl)imino)-N,N-diethylhexahydro-1,3-dimethyl-2lambda5-1,3,2-diazaphosphorin-2-amineHCID 586148106-Chloro-N-[4-chloro-3-(pyridin-2-yl)phenyl]pyridine-3-carboxamide

Product 1

HCID 58614869N-(4-chloro-3-(pyridin-2-yl)phenyl)-6-(methylsulfonamido)nicotinamide

Sources & evidence

ORD record
ord-fc47b28fea6245c39d4d5fcce5e2009f
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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