1,1-Dimethylethyl 4-{[5-methyl-4-methoxy-2-nitrophenyl]amino}-1-piperidinecarboxylate → Tert-butyl 4-(2-amino-4-methoxy-5-methylanilino)piperidine-1-carboxylate
Reaction equation
[CH3:1][c:2]1[c:3]([O:25][CH3:26])[cH:4][c:5]([N+:22]([O-:23])=[O:24])[c:6]([NH:8][CH:9]2[CH2:10][CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]2)[cH:7]1.[NH2:27][c:28]1[cH:29][c:30]([F:31])[c:32]([CH3:33])[cH:34][c:35]1[NH:36][CH:37]1[CH2:38][CH2:39][N:40]([C:41]([O:42][C:43]([CH3:44])([CH3:45])[CH3:46])=[O:47])[CH2:48][CH2:49]1>>[CH3:1][c:2]1[c:3]([O:25][CH3:26])[cH:4][c:5]([NH2:22])[c:6]([NH:8][CH:9]2[CH2:10][CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]2)[cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-5f62d7a42d8c4501a9a4e4057f75f9b6
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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