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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 959651Generated: November 1, 2026

Water → (3,5-Bis-trifluoromethyl-benzyl)-(5-bromo-pyrimidin-2-yl)-(5'-isopropyl-2'-methoxy-4-trifluoromethyl-biphenyl-2-ylmethyl)-amine

https://huagongshe.com/reaction/959651

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantTolueneHCID 1140—
ReactantDiisopropylethylamineHCID 81531—
Reactant5-Bromo-2-chloropyrimidineHCID 606665—
Reactant[3,5-Bis(trifluoromethyl)benzyl]{[5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methyl}amineHCID 59343883—
Product(3,5-Bis-trifluoromethyl-benzyl)-(5-bromo-pyrimidin-2-yl)-(5'-isopropyl-2'-methoxy-4-trifluoromethyl-biphenyl-2-ylmethyl)-amineHCID 86626868—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-68167488fbef4523bb1232496ddabc82
Source noteValidation data from https://doi.org/10.1039/C8SC04228D