Dichloromethane → 4-(4-Fluorobenzyl)-3-oxopiperazine-1-carbonitrile
Reaction equation
[CH2:19]([Cl:20])[Cl:21].[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][N:7]2[C:8](=[O:13])[CH2:9][NH:10][CH2:11][CH2:12]2)[cH:14][cH:15]1.[N:16]#[C:17][Br:18]>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][N:7]2[C:8](=[O:13])[CH2:9][N:10]([C:17]#[N:16])[CH2:11][CH2:12]2)[cH:14][cH:15]1Participants
4
Sources & evidence
- ORD record
- ord-6402617858d749a0946600f8a896daf7
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…