3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline → N-[3-(2-methylimidazol-1-yl)-5-trifluoromethyl-phenyl]-4-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide
Reaction equation
[CH3:18][c:19]1[n:20][cH:21][n:22](-[c:23]2[cH:24][c:25]([NH2:26])[cH:27][c:28]([C:29]([F:30])([F:31])[F:32])[cH:33]2)[cH:34]1.[CH3:1][c:2]1[n:3](-[c:7]2[cH:8][c:9]([NH2:17])[cH:10][c:11]([C:13]([F:14])([F:15])[F:16])[cH:12]2)[cH:4][cH:5][n:6]1.[n:35]1[cH:36][c:37](-[c:41]2[n:42][c:43]([NH:47][c:48]3[cH:49][cH:50][c:51]([C:52](=[O:53])[OH:54])[cH:55][cH:56]3)[n:44][cH:45][cH:46]2)[cH:38][cH:39][cH:40]1>>[CH3:1][c:2]1[n:3](-[c:7]2[cH:8][c:9]([NH:17][C:52]([c:51]3[cH:50][cH:49][c:48]([NH:47][c:43]4[n:42][c:41](-[c:37]5[cH:36][n:35][cH:40][cH:39][cH:38]5)[cH:46][cH:45][n:44]4)[cH:56][cH:55]3)=[O:53])[cH:10][c:11]([C:13]([F:14])([F:15])[F:16])[cH:12]2)[cH:4][cH:5][n:6]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-081c593fe0f54ec2962afef6c0dfb934
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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