Acetonitrile → 4-Methyl-1-(4-trifluoromethyl-pyrimidin-2-yl)-piperidin-4-ylamine
Reaction equation
[CH2:1]([O:2][C:3](=[O:4])[NH:10][C:11]1([CH3:27])[CH2:12][CH2:13][N:14]([c:17]2[n:18][cH:19][cH:20][c:21]([C:23]([F:24])([F:25])[F:26])[n:22]2)[CH2:15][CH2:16]1)[c:5]1[cH:6][cH:7][cH:8][cH:9][cH:28]1.[CH3:29][C:30]#[N:31]>>[NH2:10][C:11]1([CH3:27])[CH2:12][CH2:13][N:14]([c:17]2[n:18][cH:19][cH:20][c:21]([C:23]([F:24])([F:25])[F:26])[n:22]2)[CH2:15][CH2:16]1Participants
3
Sources & evidence
- ORD record
- ord-f183e57b9f0442d19c3518649e770132
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…