Ethanol → N-(5-amino-2-(2,6-dimethylpyrimidin-4-ylamino)pyridine-4-yl)-2,6-dichlorobenzamide

HRID 959865Notes

Reaction equation

HRID 959865 reaction equation
[CH3:30][CH2:31][OH:32].[Cl:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][c:7]2[cH:8][c:9]([NH:16][c:17]3[n:18][c:19]([CH3:24])[n:20][c:21]([CH3:23])[cH:22]3)[n:10][cH:11][c:12]2[N+:13]([O-:14])=[O:15])[c:25]([Cl:29])[cH:26][cH:27][cH:28]1.[Pd:33]>>[Cl:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][c:7]2[cH:8][c:9]([NH:16][c:17]3[n:18][c:19]([CH3:24])[n:20][c:21]([CH3:23])[cH:22]3)[n:10][cH:11][c:12]2[NH2:13])[c:25]([Cl:29])[cH:26][cH:27][cH:28]1

Participants

4

Reactant 3

HCID 702EthanolHCID 23938PalladiumHCID 671286552,6-dichloro-N-(2-(2,6-dimethylpyrimidin-4-ylamino)-5-nitropyridine-4-yl)benzoamide

Product 1

HCID 59618403N-(5-amino-2-(2,6-dimethylpyrimidin-4-ylamino)pyridine-4-yl)-2,6-dichlorobenzamide

Sources & evidence

ORD record
ord-75bcc58ba9de4c239ec9063fefed964e
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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