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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 959904Generated: October 27, 2026

1,2-Dichloroethane → Methyl 3-[[4-[[5-cyclohexyl-3-[4-(trifluoromethoxy)phenyl]pyrazol-1-yl]methyl]benzoyl]amino]-2-hydroxypropanoate

https://huagongshe.com/reaction/959904

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantHydrochloric AcidHCID 313—
ReactantDimethylformamideHCID 6228—
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantDiisopropylethylamineHCID 81531—
ReactantMethyl 3-amino-2-hydroxypropanoateHCID 11105589—
Reactant4-({5-Cyclohexyl-3-[4-(trifluoromethoxy)phenyl]-1H-pyrazol-1-yl}methyl)benzoic acidHCID 67335063—
ProductMethyl 3-[[4-[[5-cyclohexyl-3-[4-(trifluoromethoxy)phenyl]pyrazol-1-yl]methyl]benzoyl]amino]-2-hydroxypropanoateHCID 10256870—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-31656ff2634d475b9d2f53358de19fa0
Source noteValidation data from https://doi.org/10.1039/C8SC04228D