3-Chloro-1H-indole-6-carboxylic acid → 4-{2-[(3-Chloro-1H-indole-6-carbonyl)amino]-2-cyclopentyl-ethoxymethyl}piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([CH2:14][O:15][CH2:16][CH:17]([CH:18]2[CH2:19][CH2:20][CH2:21][CH2:22]2)[NH2:23])[CH2:12][CH2:13]1.[Cl:24][c:25]1[cH:26][nH:27][c:28]2[cH:29][c:30]([C:34](=[O:35])[OH:36])[cH:31][cH:32][c:33]12>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([CH2:14][O:15][CH2:16][CH:17]([CH:18]2[CH2:19][CH2:20][CH2:21][CH2:22]2)[NH:23][C:34]([c:30]2[cH:29][c:28]3[nH:27][cH:26][c:25]([Cl:24])[c:33]3[cH:32][cH:31]2)=[O:35])[CH2:12][CH2:13]1Participants
3
Sources & evidence
- ORD record
- ord-4720a6009b9f4aa389a4c62b5d5758a5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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