Dimethyl Sulfoxide → 5,6-Dimethoxy-1-(4-nitrophenyl)-indoline

HRID 960216Notes

Reaction equation

HRID 960216 reaction equation
[C:24](=[O:25])([O-:26])[OH:27].[CH3:11][O:12][c:13]1[cH:14][c:15]2[c:19]([cH:20][c:21]1[O:22][CH3:23])[NH:18][CH2:17][CH2:16]2.[CH3:29][S:30]([CH3:31])=[O:32].[N+:1](=[O:2])([O-:3])[c:4]1[cH:5][cH:6][c:7]([F:10])[cH:8][cH:9]1.[Na+:28]>>[N+:1](=[O:2])([O-:3])[c:4]1[cH:5][cH:6][c:7]([N:18]2[CH2:17][CH2:16][c:15]3[cH:14][c:13]([O:12][CH3:11])[c:21]([O:22][CH3:23])[cH:20][c:19]32)[cH:8][cH:9]1

Participants

6

Reactant 5

HCID 679Dimethyl SulfoxideHCID 769Bicarbonate IonHCID 923Sodium ionHCID 9590p-FluoronitrobenzeneHCID 110629785,6-Dimethoxyindoline

Product 1

HCID 227173945,6-Dimethoxy-1-(4-nitrophenyl)-indoline

Sources & evidence

ORD record
ord-5f129ab6d67c4a67807789e50968b0a4
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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