Pyridine → tert-butyl N-[1-[5-bromo-3-(ethylcarbamoylamino)-1H-pyrrolo[2,3-b]pyridin-4-yl]piperidin-3-yl]carbamate
Reaction equation
[N:26](=[C:27]=[O:28])[CH2:29][CH3:30].[NH2:1][c:2]1[cH:3][nH:4][c:5]2[n:6][cH:7][c:8]([Br:25])[c:9]([N:11]3[CH2:12][CH:13]([NH:17][C:18]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[CH2:14][CH2:15][CH2:16]3)[c:10]12.[cH:31]1[cH:32][cH:33][n:34][cH:35][cH:36]1>>[NH:1]([c:2]1[cH:3][nH:4][c:5]2[n:6][cH:7][c:8]([Br:25])[c:9]([N:11]3[CH2:12][CH:13]([NH:17][C:18]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[CH2:14][CH2:15][CH2:16]3)[c:10]12)[C:27]([NH:26][CH2:29][CH3:30])=[O:28]Participants
4
Sources & evidence
- ORD record
- ord-b6a05bdf01c64e399770f45b9efb7de5
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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