2-Methylbenzoic acid → 2-Methyl-N-propyl-N-[3,3,3-trifluoro-2-({[1-(4-fluorophenyl)-1H-indazol-4-yl]amino}methyl)-2-hydroxypropyl]benzamide
Reaction equation
[CH3:1][c:2]1[cH:3][cH:4][cH:5][cH:6][c:7]1[C:8]([OH:9])=[O:10].[F:11][C:12]([C:13]([CH2:14][NH:15][c:16]1[c:17]2[cH:18][n:19][n:20](-[c:25]3[cH:26][cH:27][c:28]([F:31])[cH:29][cH:30]3)[c:21]2[cH:22][cH:23][cH:24]1)([OH:32])[CH2:33][NH:34][CH2:35][CH2:36][CH3:37])([F:38])[F:39]>>[CH3:1][c:2]1[cH:3][cH:4][cH:5][cH:6][c:7]1[C:8](=[O:10])[N:34]([CH2:33][C:13]([C:12]([F:11])([F:38])[F:39])([CH2:14][NH:15][c:16]1[c:17]2[cH:18][n:19][n:20](-[c:25]3[cH:26][cH:27][c:28]([F:31])[cH:29][cH:30]3)[c:21]2[cH:22][cH:23][cH:24]1)[OH:32])[CH2:35][CH2:36][CH3:37]Participants
3
Sources & evidence
- ORD record
- ord-7e943bedb5ef4309bbc8ae928cf63478
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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