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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 960559Generated: October 29, 2026

Acetonitrile → 4,4-Difluoro-pyrrolidine-1,2-dicarboxylic acid 2-[2-(6-bromo-naphthalen-2-yl)-2-oxo-ethyl]ester 1-tert-butyl ester

https://huagongshe.com/reaction/960559

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetonitrileHCID 6342—
ReactantTriethylamineHCID 8471—
Reactant2-Bromo-1-(6-bromonaphthalen-2-yl)ethanoneHCID 12698898—
Reactant1-((Tert-butoxy)carbonyl)-4,4-difluoropyrrolidine-2-carboxylic acidHCID 23512514—
Product4,4-Difluoro-pyrrolidine-1,2-dicarboxylic acid 2-[2-(6-bromo-naphthalen-2-yl)-2-oxo-ethyl]ester 1-tert-butyl esterHCID 66620864—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-3f03d316facf4ca8b77601e9d2a5122b
Source noteValidation data from https://doi.org/10.1039/C8SC04228D