3-(Trifluoromethyl)phenyl chloroformate → 3-(Trifluoromethyl)phenyl 4-(prop-2-ynyl)piperidine-1-carboxylate

HRID 960619Notes

Reaction equation

HRID 960619 reaction equation
[CH2:15]([C:16]#[CH:17])[CH:18]1[CH2:19][CH2:20][N:21]([C:24]([O:25][C:26]([CH3:27])([CH3:28])[CH3:29])=[O:30])[CH2:22][CH2:23]1.[Cl:1][C:2](=[O:3])[O:4][c:5]1[cH:6][c:7]([C:11]([F:12])([F:13])[F:14])[cH:8][cH:9][cH:10]1>>[C:2](=[O:3])([O:4][c:5]1[cH:6][c:7]([C:11]([F:12])([F:13])[F:14])[cH:8][cH:9][cH:10]1)[N:21]1[CH2:20][CH2:19][CH:18]([CH2:15][C:16]#[CH:17])[CH2:23][CH2:22]1

Participants

3

Reactant 2

HCID 50574253-(Trifluoromethyl)phenyl chloroformateHCID 18187546Tert-butyl 4-(prop-2-yn-1-yl)piperidine-1-carboxylate

Product 1

HCID 578389003-(Trifluoromethyl)phenyl 4-(prop-2-ynyl)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-39d1deff81244380ad161413b8b7cece
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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