tert-Butanol → 4-(4,5-dimethylthiophen-2-yl)-N-(4-(7-methoxy-1,5-naphthyridin-4-yloxy)phenyl)phthalazin-1-amine
Reaction equation
[CH3:19][O:20][c:21]1[cH:22][n:23][c:24]2[c:25]([O:31][c:32]3[cH:33][cH:34][c:35]([NH2:38])[cH:36][cH:37]3)[cH:26][cH:27][n:28][c:29]2[cH:30]1.[CH3:39][C:40]([OH:41])([CH3:42])[CH3:43].[Cl:1][c:2]1[n:3][n:4][c:5](-[c:12]2[s:13][c:14]([CH3:18])[c:15]([CH3:17])[cH:16]2)[c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]12>>[c:2]1([NH:38][c:35]2[cH:34][cH:33][c:32]([O:31][c:25]3[c:24]4[n:23][cH:22][c:21]([O:20][CH3:19])[cH:30][c:29]4[n:28][cH:27][cH:26]3)[cH:37][cH:36]2)[n:3][n:4][c:5](-[c:12]2[s:13][c:14]([CH3:18])[c:15]([CH3:17])[cH:16]2)[c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]12Participants
4
Sources & evidence
- ORD record
- ord-0a5c4ec9243e4b9dbb245f9e38340226
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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