Dichloromethane → 1-(4,4-dimethyl-3,4-dihydroisoquinolin-2(1H)-yl)ethanone

HRID 960746Notes

Reaction equation

[CH3:1][C:2]([O:3][C:5]([CH3:6])=[O:7])=[O:4].[CH3:8][C:9]1([CH3:19])[CH2:10][NH:11][CH2:12][c:13]2[cH:14][cH:15][cH:16][cH:17][c:18]21.[Cl:20][CH2:21][Cl:22]>>[C:5]([CH3:6])(=[O:7])[N:11]1[CH2:10][C:9]([CH3:8])([CH3:19])[c:18]2[c:13]([cH:14][cH:15][cH:16][cH:17]2)[CH2:12]1

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 7918Acetic Anhydride

HCID 1921721,2,3,4-Tetrahydro-4,4-dimethylisoquinoline

Product 1

HCID 225920161-(4,4-dimethyl-3,4-dihydroisoquinolin-2(1H)-yl)ethanone

Sources & evidence

ORD record: ord-25d74767323b435b8623875334ae048a
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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