Ammonium → Tert-butyl 4-(3-amino-5-bromopyrazin-2-yl)piperazine-1-carboxylate
Reaction equation
[Br:1][c:2]1[n:3][c:4]([Cl:21])[c:5]([N:8]2[CH2:9][CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[n:6][cH:7]1.[NH4+:22].[OH-:23].[OH2:24]>>[Br:1][c:2]1[n:3][c:4]([NH2:22])[c:5]([N:8]2[CH2:9][CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[n:6][cH:7]1Participants
5
Sources & evidence
- ORD record
- ord-c12a1e0c520c48a8999b93eccfa57707
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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