Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 960852Generated: October 30, 2026

Dichloromethane → [5-(2-Amino-1-hydroxy-ethyl)-thiazol-2-yl]-carbamic acid tert-butyl ester

https://huagongshe.com/reaction/960852

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantIodide IonHCID 30165—
ReactantZinc(2+)HCID 32051—
ReactantTrimethylsilyl cyanideHCID 82115—
Reactanttert-butyl N-(5-formyl-1,3-thiazol-2-yl)carbamateHCID 53393345—
Product[5-(2-Amino-1-hydroxy-ethyl)-thiazol-2-yl]-carbamic acid tert-butyl esterHCID 86603181—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-cbb9f887156d47458d83149b96a24cd6
Source noteValidation data from https://doi.org/10.1039/C8SC04228D