2-Thiophenecarbonyl chloride → [3-Hydroxy-3-(3-methoxyphenyl)-piperidine-1-yl]-thiophen-2-yl-methanone

HRID 96094Notes

Reaction equation

HRID 96094 reaction equation
[CH3:9][O:10][c:11]1[cH:12][c:13]([C:17]2([OH:23])[CH2:18][NH:19][CH2:20][CH2:21][CH2:22]2)[cH:14][cH:15][cH:16]1.[s:1]1[c:2]([C:6](=[O:7])[Cl:8])[cH:3][cH:4][cH:5]1>>[s:1]1[c:2]([C:6](=[O:7])[N:19]2[CH2:18][C:17]([c:13]3[cH:12][c:11]([O:10][CH3:9])[cH:16][cH:15][cH:14]3)([OH:23])[CH2:22][CH2:21][CH2:20]2)[cH:3][cH:4][cH:5]1

Participants

3

Reactant 2

HCID 789282-Thiophenecarbonyl chlorideHCID 116516763-(3-Methoxy-phenyl)-piperidine-3-ol

Product 1

HCID 11536987[3-Hydroxy-3-(3-methoxyphenyl)-piperidine-1-yl]-thiophen-2-yl-methanone

Sources & evidence

ORD record
ord-12179bbcf85241d2afbebd773022e32f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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