Ethanol → (5S)-{[(tert-butyl)dimethylsilyloxy]methyl}-2-pyrrolidinone
Reaction equation
[CH3:30][CH2:31][OH:32].[F:1][c:2]1[cH:3][c:4]([N:9]2[C:10](=[O:26])[O:11][CH:12]([CH2:14][N:15]3[C:16](=[O:17])[c:18]4[c:19]([cH:20][cH:21][cH:22][cH:23]4)[C:24]3=[O:25])[CH2:13]2)[cH:5][cH:6][c:7]1[I:8].[NH2:28][NH2:29].[OH2:27]>>[F:1][c:2]1[cH:3][c:4]([N:9]2[C:10](=[O:26])[O:11][CH:12]([CH2:14][NH2:15])[CH2:13]2)[cH:5][cH:6][c:7]1[I:8]Participants
5
Sources & evidence
- ORD record
- ord-1423f98e844d410dafb5defbea2da1e9
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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