Methanol → 5-(2-Fluoro-4-{[2-(2-fluorophenyl)ethylamino]methyl}phenoxy)pyridine-2-carboxamide
Reaction equation
[BH4-:33].[CH3:35][OH:36].[F:23][c:24]1[c:25]([CH2:26][CH2:27][NH2:28])[cH:29][cH:30][cH:31][cH:32]1.[Na+:34].[O:1]1[CH:2]([c:6]2[cH:7][c:8]([F:22])[c:9]([O:10][c:11]3[cH:12][cH:13][c:14]([C:17](=[O:18])[NH2:19])[n:15][cH:16]3)[cH:20][cH:21]2)[O:5][CH2:4][CH2:3]1>>[CH2:2]([c:6]1[cH:7][c:8]([F:22])[c:9]([O:10][c:11]2[cH:12][cH:13][c:14]([C:17](=[O:18])[NH2:19])[n:15][cH:16]2)[cH:20][cH:21]1)[NH:28][CH2:27][CH2:26][c:25]1[c:24]([F:23])[cH:32][cH:31][cH:30][cH:29]1Participants
6
Sources & evidence
- ORD record
- ord-a93ff03264bd41cfab0fbcc67d5af320
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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