Ammonia → 9-(3-(2-(tert-Butyldimethylsilyloxy)ethyl)-2-fluorobenzyl)-1-oxa-4,9-diazaspiro[5.5]undecane
Reaction equation
[C:2]([CH3:3])([CH3:4])([CH3:5])[Si:6]([O:7][CH2:8][CH2:9][c:10]1[c:11]([F:34])[c:12]([CH2:13][N:14]2[CH2:15][CH2:16][C:17]3([CH2:18][N:19]([C:23](=[O:24])[C:25]([F:26])([F:27])[F:28])[CH2:20][CH2:21][O:22]3)[CH2:29][CH2:30]2)[cH:31][cH:32][cH:33]1)([CH3:35])[CH3:36].[CH3:37][OH:38].[NH3:1]>>[C:2]([CH3:3])([CH3:4])([CH3:5])[Si:6]([O:7][CH2:8][CH2:9][c:10]1[c:11]([F:34])[c:12]([CH2:13][N:14]2[CH2:15][CH2:16][C:17]3([CH2:18][NH:19][CH2:20][CH2:21][O:22]3)[CH2:29][CH2:30]2)[cH:31][cH:32][cH:33]1)([CH3:35])[CH3:36]Participants
4
Sources & evidence
- ORD record
- ord-ca7d9e2ac8644f17bf2a0f5b8d2a014b
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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