Water → 5-amino-6,8-difluoro-2-(3-fluoro-4-pivaloylaminophenyl)-4H-1-benzopyran-4-one

HRID 961236Notes

Reaction equation

[C:23]([C:24]([CH3:25])([CH3:26])[CH3:27])(=[O:28])[Cl:29].[NH2:1][c:2]1[c:3]([F:22])[cH:4][c:5]([F:21])[c:6]2[c:7]1[c:8](=[O:20])[cH:9][c:10](-[c:12]1[cH:13][c:14]([F:19])[c:15]([NH2:18])[cH:16][cH:17]1)[o:11]2.[OH2:30].[cH:31]1[cH:32][cH:33][n:34][cH:35][cH:36]1>>[NH2:1][c:2]1[c:3]([F:22])[cH:4][c:5]([F:21])[c:6]2[c:7]1[c:8](=[O:20])[cH:9][c:10](-[c:12]1[cH:13][c:14]([F:19])[c:15]([NH:18][C:23]([C:24]([CH3:25])([CH3:26])[CH3:27])=[O:28])[cH:16][cH:17]1)[o:11]2