Water → 1-Amino-4-bromo-6-fluoro-isoquinoline
Reaction equation
[Cl:22][CH:23]([Cl:24])[Cl:25].[NH2:1][c:2]1[n:3][cH:4][cH:5][c:6]2[cH:7][c:8]([F:12])[cH:9][cH:10][c:11]12.[O:13]=[C:14]1[N:15]([Br:20])[C:16](=[O:17])[CH2:18][CH2:19]1.[OH2:21]>>[NH2:1][c:2]1[n:3][cH:4][c:5]([Br:20])[c:6]2[cH:7][c:8]([F:12])[cH:9][cH:10][c:11]12Participants
5
Sources & evidence
- ORD record
- ord-6247718b97434c89b5c28c5b9d6b82dd
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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