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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 961756Generated: October 31, 2026

Dimethylformamide → 3-(difluoromethyl)-5-methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole-4-carbaldehyde

https://huagongshe.com/reaction/961756

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantTetrahydrofuranHCID 8028—
ReactantHexaneHCID 8058—
Reactant4-bromo-3-(difluoromethyl)-5-methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazoleHCID 66887014—
ReactantButyllithiumHCID 178418339—
Product3-(difluoromethyl)-5-methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole-4-carbaldehydeHCID 86613273—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-e42b01ec45404106931e05dde5d1e3b6
Source noteValidation data from https://doi.org/10.1039/C8SC04228D