HCID 58313095, compound → methyl N-[1-[2-[5-[4-[4-[2-[(1-acetyl-8-oxa-1-azaspiro[4.5]decane-2-carbonyl)amino]acetyl]phenyl]phenyl]-1H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate

HRID 96181Notes

Reaction equation

HRID 96181 reaction equation
[C:1]([CH3:2])(=[O:3])[N:4]1[CH:5]([C:14](=[O:15])[OH:16])[CH2:6][CH2:7][C:8]12[CH2:9][CH2:10][O:11][CH2:12][CH2:13]2.[CH3:17][CH:18]([CH3:19])[CH:20]([NH:21][C:22]([O:23][CH3:24])=[O:25])[C:26]([N:27]1[CH:28]([C:29](=[O:30])[NH:39][CH2:40][C:41](=[O:42])[c:43]2[cH:44][cH:45][c:46](-[c:49]3[cH:50][cH:51][c:52](-[c:55]4[n:56][c:57]([CH:60]5[N:61]([C:65]([CH:66]([CH:67]([CH3:68])[CH3:69])[NH:70][C:71](=[O:72])[O:73][CH3:74])=[O:75])[CH2:62][CH2:63][CH2:64]5)[nH:58][cH:59]4)[cH:53][cH:54]3)[cH:47][cH:48]2)[CH2:31][C:32]2([CH2:33][N:34]([C:35]([O:36][C:37]([CH3:38])([CH3:76])[CH3:77])=[O:78])[CH2:79]2)[CH2:80]1)=[O:81]>>[C:1]([CH3:2])(=[O:3])[N:4]1[CH:5]([C:14](=[O:16])[NH:39][CH2:40][C:41](=[O:42])[c:43]2[cH:44][cH:45][c:46](-[c:49]3[cH:50][cH:51][c:52](-[c:55]4[n:56][c:57]([CH:60]5[N:61]([C:65]([CH:66]([CH:67]([CH3:68])[CH3:69])[NH:70][C:71](=[O:72])[O:73][CH3:74])=[O:75])[CH2:62][CH2:63][CH2:64]5)[nH:58][cH:59]4)[cH:53][cH:54]3)[cH:47][cH:48]2)[CH2:6][CH2:7][C:8]12[CH2:9][CH2:10][O:11][CH2:12][CH2:13]2

Participants

3

Reactant 2

HCID 58313095HCID 58313095, compoundHCID 178502139tert-butyl 6-[2-(methoxycarbonylamino)-3-methylbutanoyl]-7-[[2-[4-[4-[2-[1-[2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidin-2-yl]-1H-imidazol-5-yl]phenyl]phenyl]-2-oxoethyl]carbamoyl]-2,6-diazaspiro[3.4]octane-2-carboxylate

Product 1

HCID 178502172methyl N-[1-[2-[5-[4-[4-[2-[(1-acetyl-8-oxa-1-azaspiro[4.5]decane-2-carbonyl)amino]acetyl]phenyl]phenyl]-1H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate

Sources & evidence

ORD record
ord-84e5b67266ae40e9943b82939b1ea1ec
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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