Acetonitrile → 5-Bromo-3-(2,6-dichloro-3-fluoro-benzyloxy)-pyridin-2-ylamine
Reaction equation
[Br:19][N:20]1[C:21](=[O:22])[CH2:23][CH2:24][C:25]1=[O:26].[CH3:27][C:28]#[N:29].[Cl:1][c:2]1[c:3]([CH2:4][O:5][c:6]2[c:7]([NH2:12])[n:8][cH:9][cH:10][cH:11]2)[c:13]([Cl:18])[cH:14][cH:15][c:16]1[F:17]>>[Cl:1][c:2]1[c:3]([CH2:4][O:5][c:6]2[c:7]([NH2:12])[n:8][cH:9][c:10]([Br:19])[cH:11]2)[c:13]([Cl:18])[cH:14][cH:15][c:16]1[F:17]Participants
4
Sources & evidence
- ORD record
- ord-87c2e8f9796441438fc08d21e43fe05a
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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