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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 962025Generated: October 31, 2026

Hydrochloric Acid → 8-(6-chloro-5-fluoro-2-methylpyrimidin-4-yl)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[2,1-c][1,4]oxazine

https://huagongshe.com/reaction/962025

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDichloromethaneHCID 6344—
ReactantDiisopropylethylamineHCID 81531—
Reactant4,6-Dichloro-5-fluoro-2-methylpyrimidineHCID 13731033—
ReactantOctahydropiperazino[2,1-c]morpholineHCID 19777228—
Product8-(6-chloro-5-fluoro-2-methylpyrimidin-4-yl)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[2,1-c][1,4]oxazineHCID 90422601—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-9f5177b94cfb481b92e2ea8deaaf79e5
Source noteValidation data from https://doi.org/10.1039/C8SC04228D