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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 962117Generated: October 30, 2026

Toluene → 2'-Fluoro-2-isopropylsulfanyl-5'-methoxy-biphenyl-4-carboxylic acid methyl ester

https://huagongshe.com/reaction/962117

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTolueneHCID 1140—
Reactant2-PropanethiolHCID 6364—
ReactantPalladiumHCID 23938—
ReactantDiisopropylethylamineHCID 81531—
ReactantDibenzylidene acetoneHCID 95417—
Reactant1,1'-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(1,1-diphenylphosphine)HCID 636044—
ReactantMethyl 2'-fluoro-2-iodo-5'-(methyloxy)-1,1'-biphenyl-4-carboxylateHCID 57705628—
Product2'-Fluoro-2-isopropylsulfanyl-5'-methoxy-biphenyl-4-carboxylic acid methyl esterHCID 57467638—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-4712d5506651421da50d6c8d59d3af2d
Source noteValidation data from https://doi.org/10.1039/C8SC04228D