Acetonitrile → 4-(4'-Difluoromethoxy-biphenyl-4-ylaminomethyl)-5-methylfuran-2-carboxylic acid methyl ester
Reaction equation
[CH3:1][O:2][C:3](=[O:4])[c:5]1[o:6][c:7]([CH3:12])[c:8]([CH2:10][Cl:11])[cH:9]1.[CH3:30][C:31]#[N:32].[F:13][CH:14]([O:15][c:16]1[cH:17][cH:18][c:19](-[c:22]2[cH:23][cH:24][c:25]([NH2:28])[cH:26][cH:27]2)[cH:20][cH:21]1)[F:29]>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[o:6][c:7]([CH3:12])[c:8]([CH2:10][NH:28][c:25]2[cH:24][cH:23][c:22](-[c:19]3[cH:18][cH:17][c:16]([O:15][CH:14]([F:13])[F:29])[cH:21][cH:20]3)[cH:27][cH:26]2)[cH:9]1Participants
4
Sources & evidence
- ORD record
- ord-4c5103063412425cb88697afe520bc01
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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