Water → tert-Butyl methyl(1-(5-(thiophen-2-yl)tetrazolo[1,5-a]pyrazin-8-yl)azetidin-3-yl)carbamate

HRID 962266Notes

Reaction equation

[Br:1][c:2]1[cH:3][n:4][c:5]([N:11]2[CH2:12][CH:13]([N:15]([C:16]([O:17][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:22])[CH3:23])[CH2:14]2)[c:6]2[n:7]1[n:8][n:9][n:10]2.[C:32](=[O:33])([O-:34])[O-:35].[CH2:38]1[O:39][CH2:40][CH2:41][O:42][CH2:43]1.[Cs+:36].[Cs+:37].[OH2:121].[cH:44]1[cH:45][cH:46][c:47]([P:48]([Pd:49]([P:50]([c:51]2[cH:52][cH:53][cH:54][cH:55][cH:56]2)([c:57]2[cH:58][cH:59][cH:60][cH:61][cH:62]2)[c:63]2[cH:64][cH:65][cH:66][cH:67][cH:68]2)([P:69]([c:70]2[cH:71][cH:72][cH:73][cH:74][cH:75]2)([c:76]2[cH:77][cH:78][cH:79][cH:80][cH:81]2)[c:82]2[cH:83][cH:84][cH:85][cH:86][cH:87]2)[P:88]([c:89]2[cH:90][cH:91][cH:92][cH:93][cH:94]2)([c:95]2[cH:96][cH:97][cH:98][cH:99][cH:100]2)[c:101]2[cH:102][cH:103][cH:104][cH:105][cH:106]2)([c:107]2[cH:108][cH:109][cH:110][cH:111][cH:112]2)[c:113]2[cH:114][cH:115][cH:116][cH:117][cH:118]2)[cH:119][cH:120]1.[s:24]1[c:25]([B:29]([OH:30])[OH:31])[cH:26][cH:27][cH:28]1>>[c:2]1(-[c:25]2[s:24][cH:28][cH:27][cH:26]2)[cH:3][n:4][c:5]([N:11]2[CH2:12][CH:13]([N:15]([C:16]([O:17][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:22])[CH3:23])[CH2:14]2)[c:6]2[n:7]1[n:8][n:9][n:10]2