Methanol → 4-[2-Hydroxy-3-[4-(tert-butoxycarbonyl)-1-piperazinyl]propoxy]benzylcyanide
Reaction equation
[C:15]([CH3:16])([CH3:17])([CH3:18])[O:19][C:20](=[O:21])[N:22]1[CH2:23][CH2:24][NH:25][CH2:26][CH2:27]1.[CH3:28][OH:29].[O:1]1[CH:2]([CH2:3][O:4][c:5]2[cH:6][cH:7][c:8]([CH2:9][C:10]#[N:11])[cH:12][cH:13]2)[CH2:14]1>>[OH:1][CH:2]([CH2:3][O:4][c:5]1[cH:6][cH:7][c:8]([CH2:9][C:10]#[N:11])[cH:12][cH:13]1)[CH2:14][N:25]1[CH2:24][CH2:23][N:22]([C:20]([O:19][C:15]([CH3:16])([CH3:17])[CH3:18])=[O:21])[CH2:27][CH2:26]1Participants
4
Sources & evidence
- ORD record
- ord-8daaaf9dab3d4f0395b80bc42a75dde7
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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